WebMD Medical News
Daniel J. DeNoon
Brunilda Nazario, MD
Feb. 1, 2010 - Five simple questions can help you find out whether your
child needs a gluten-free diet, Danish researchers suggest.
Many children have celiac disease, a disorder that causes damage to the
intestines when food containing gluten is eaten. Such kids do much better on a
gluten-free diet. Foods containing wheat, oats, and barley give them
But at least half of kids with celiac disease never get diagnosed, and thus
needlessly suffer symptoms such as diarrhea, abdominal pain, and behavior
There's a blood test that tells doctors which kids likely have celiac
disease. But it's impractical to give all kids the blood test. Might it be
easier to test only kids who have one or more symptoms of celiac disease?
To find out, Peter Toftedal, MD, of Odense University Hospital, Denmark,
created a questionnaire for parents. The five items elicit information on
recurrent abdominal pain, chronic diarrhea, constipation, and lack of height
and weight gain:
How well does it work? Toftedal and colleagues tested the questionnaire on
Denmark's County of Funen. They mailed it to the parents of 9,880 8- and
9-year-olds. Before giving the questionnaire, 13 Funen kids were known to have
Of the 7,029 parents who filled out the questionnaire, 2,835 reported at
least one symptom. All of these kids were invited for a blood test. Of the
1,720 children tested, 24 were positive for the antibodies characteristic of
Further tests identified 14 kids with celiac disease. That means that in
Funen, only half of the kids with celiac disease had been diagnosed.
"A number of preclinical and low-grade symptomatic patients with celiac
disease may be identified by their responses to a mailed questionnaire,"
Toftedal and colleagues conclude.
The findings appear in the March issue of Pediatrics.
SOURCE:Toftedal, P. Pediatrics, March 2010; vol: 125; manuscript received
ahead of print.
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